Clinical trials - recruiting subjects
The ADP Consultancy conducts clinical trials for the purpose of increasing our knowledge in the field of eye care. We hope to have trials under way in 2021 looking at an in-practice treatment for contact lens discomfort and/or at home therapy for dry eye, if you think you would like to find out more about how you might help, or may be interested in future trials and live within traveling distance of Nantwich, Southport, Sheffield, Chestefield, Wakefield or in the Berks/Hants/Surrey region please email
Contact Lens Discomfort Trial - at-home Treatment
20/07/2021: The ADP Consultancy conducts clinical trials for the purpose of increasing our knowledge in the field of eye care. We hope to have a trial under way soon looking at-home treatments for contact lens discomfort, if you think you would like to find out more about how you might help, or may be interested in future trials and live within traveling distance of Nantwich. We are looking for subjects who find their contact lenses are not as comfortable as they would like, especially at the end of the day. The trial does not involve changing lenses or solutions. The object of the clinical trial is to determine if a specific at-home treatment reduces contact lens discomfort. Subjects will be paid to be part of the trial and provided with all treatment products free-of-charge. If you would like to know more about this trial please email
Prevalance of Meibomian gland loss in a population
Not so much a clinical trial, but certainly reserach, as part of the normal eye exam (sight test) provided by S W & C Jackson Opticians of Nantwich, Meibomian gland screening with grading will be included at no extra charge. As well as offering more information to individual patients on their eye health it will generate fully anonymised data on the the prevelance and grading of Meibomian gland loss in both symptomatic and non-symptomatic patients. It is anticipated this will generate data on hundreds of eyes in a relatively short space of time that can help improve care of dry eye and potential dry eye patients. If you are a patient who would like to have this screening included in your next general eye exam at no extra charge email
DOORS Press Release
A new health study is to be launched in a bid to help millions who suffer from ‘dry eye’.
One in four of us will suffer from the debilitating condition with symptoms ranging from sore eyes through to short-term blurred vision.
Now experts based in Birmingham and Nottingham are looking for people to take part in the study, wearing a special contact lens for under 2 weeks, which could lead to longer term relief.
Volunteers are being sought for the research which is being conducted by Aston University’s Eye Clinic in collaboration with Nottingham’s NuVision Biotherapies, a company formed with backing of the University of Nottingham.
The study follows the development of an eyesight-saving product, Omnigen, derived from human amniotic membrane donated from caesarean sections. Up until recently it could only be applied surgically but NuVision have created OmniLenz.
This bespoke contact lens allows the surgery-free application of Omnigen. Such a simple, 5-minute procedure enables eyecare professions to treat ocular surface diseases, as simply as applying a contact lens, early and more effectively without the need for surgery.
Professor James Wolffsohn, principle investigator of the study, said: “Dry eye can be a severe, chronic and debilitating disease. Amniotic membrane has shown great promise in its management, but retention on the eye is required. We want to see how we can help people with dry eye by applying this lens.
“Omnigen is already successfully used throughout the NHS and the study aims to demonstrate that the wound healing benefits of Omnigen are easily transferable to those suffering and living with dry eye disease.”
This trial is designed as a prospective, double-arm, investigational randomised study to examine the change in dry eye disease symptoms and pathology following the in-clinic OmniLenz transplantation of Omnigen for patients suffering from moderate to severe dry eye disease.
Founder and Chief Scientific Officer of NuVision, Dr. Andrew Hopkinson, said: “Amniotic membrane has clinically proven wound healing capability which historically has been reserved for severe surgical situations. Through the innovation of OmniLenz application of Omnigen in an out-patient setting, NuVision is already helping to treat patients with severe ocular surface injuries. However, this clinical trial now aims to demonstrate a benefit to those suffering from dry eye disease.”
NuVision received support from the INSTILS project – part-funded through the European Regional Development Fund (ERDF) and delivered by Medilink East Midlands. Thanks to INSTILS support, NuVision received an Innovation Support Grant, to the value of £12,920, which will allow them to undertake this study with Aston University, accelerating the clinical trial process and bringing NuVision’s novel approach to market faster than would have otherwise been possible.
Darren Clark, Chief Executive of Medilink East Midlands, said: “NuVision has a truly innovative and outstanding approach to treating dry eye disease. I am confident that the help we’ve given to them, both in terms of the Innovation Support Grant and the dedicated time and effort that one of our Innovation Advisers has invested in them, will make their treatment available quicker, improving outcomes for patients worldwide.”
If you are interested in taking part in the study, please contact
Contact Lens Discomfort Trial - In-Practice Treatment
We are looking for subjects who find their contact lenses are not as comfortable as they would like, especially at the end of the day. The trial does not involve changing lenses or solutions but rather treating the eye's vital meibomian glands that secrete protective oils into the tears. The object of the clinical trial is to determine if, and for how long, a one-off in-practice treatment reduces contact lens discomfort. If you would like to know more about this trial please and could attend the clinics in Nantwich, Southport or Leyland please email
Made-to-Order Multifocal Contact Lens Trial
Would a 'tailor made' made-to-order multifocal lens perfor better than the equivalant widely prescribed off-the-shelf alternative? A few statistically signifianct differences were found for visual acuity and subjective vision and the overall performance of 'tailor made' lens was much better than off-the-shelf alternative. These aspects could be leveraged in a marketing campaign among contact lens practices seeking to have better overall success with multifocal soft conact lenses. 08/01/2017 Update: This trial has now completed and closed with report issued to sponsor.
Multi-Focal Contact Lens Trial (two separate trials)
We are looking for subjects who are over 42 and require different prescriptions for distance and near, bifocal/varifocal glasses, two pairs of glasses, removes distance glasses to read, glasses over contact lenses to read or monovision contact lenses. The object of the clinical trial is to determine if vision with contact lenses changes over a time period. Subjects who complete the clinical trial and are successful with the sponsor's lenses will be offered 3 months lenses free-of-charge (approx value £150.00). The subjects would be prescribed one or two pairs of lenses to wear for a week, normally three to four practice visits will be required. 05/05/2017 Update: Both of these trials has now completed and closed with report issued to sponsor.
Contact Lens Discomfort Trial
We are looking for subjects who find their contact lenses are not as comfortable as they would like, especially at the end of the day. The trial does not involve changing lenses or solutions but rather using a means to retain more tears on the eye surface. the object of the clinical trial is to determine if retaining more tears on the eye surface reduces contact lens discomfort. Subjects who complete the clinical trial will be given £100.00 practice credit. 23/12/2016 Update: This trial has now completed and closed. Interim results have been published. If you are interested in the interim results and what it may mean to you as a Contact Lens wearer email
Contact Lens Uncorrected Cyl Trial
We are looking for subjects (both CL and non-CL wearers) between 18 and 40 who have cylinder corrections up to and including -1.00 at any axis with sphere powers obtainable in daily disposable lenses. The subjects will wear both a toric and a spherical lens on two different occasions with the aim of determining if their is a objective and/or subjective visual benefit to correcting small cyls with toric lenses. Subjects who complete the trial will be offered £50 payment and £50 practice credit. For further information email